OCT Review

OCT Technologies Compared: TD, SD, EDI, Swept-Source and OCTA

Last updated: October 2026

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How the main OCT technologies differ, in one place: time-domain, spectral-domain, enhanced depth imaging, swept-source and OCT angiography. For reading the scans, see how to read an OCT and Retinal Layers & OCT Made Easy.

OCT technologies compared

TechnologyHow it worksSpeed and resolution (typical)Strengths and limits
Time-domain (TD-OCT)A moving reference mirror measures each depth one after anotherAbout 400 A-scans per second; about 10 µm axialHistorical (Stratus); slow, motion artefacts, poor choroid view
Spectral-domain (SD-OCT)All depths measured at once with a spectrometer (Fourier domain)About 20,000–85,000 A-scans per second; 5–7 µm axialMuch faster and more sensitive than TD-OCT; image averaging; choroid limited without EDI
Enhanced depth imaging (EDI-OCT)SD-OCT with the zero-delay line moved to the choroid (sensitivity is highest near the zero-delay line)As SD-OCTShows choroidal thickness (pachychoroid, VKH, tumours); image is inverted if the zero-delay line is crossed
Swept-source (SS-OCT)A tunable laser sweeps wavelengths; a photodetector records them100,000–400,000 A-scans per second; about 8 µm axial at 1050 nmDeeper penetration (vitreous to sclera), less fall-off with depth, wide scans (12 mm or more); also used for biometry
OCT angiography (OCTA)Motion contrast from moving red cells on repeated B-scans; no dyeDepends on the platformDepth-resolved plexuses, FAZ measurement, CNV detection; no leakage information, projection and motion artefacts
Anterior segment OCTLonger wavelength (1310 nm) or swept-sourcePlatform-dependentAngle, corneal thickness and epithelial maps, LASIK flaps, anterior chamber depth

Terms worth knowing

TermMeaning
A-scanOne depth profile at a single point
B-scanA cross-section made of many A-scans side by side
Axial resolutionSet by the light source bandwidth (broader band = finer resolution)
Lateral resolutionSet by the beam spot size at the retina (about 15–20 µm)
Signal strength / quality indexLow values (cataract, dry eye, small pupil) give unreliable thickness maps
Segmentation errorSoftware misplaces layer boundaries: always look at the B-scan, not just the map

Where residents slip

  • Saying SD-OCT has a lower signal-to-noise ratio than TD-OCT: it is more sensitive, which is why it replaced TD-OCT.
  • Reading a thickness map without checking the B-scans for segmentation errors.
  • Forgetting OCTA shows flow, not leakage: use FFA when leakage matters.

Related: How to read an OCT, OCT macula reference, OCT angiography, Retinal layers and OCT made easy.

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Key sources

  • Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991;254:1178-1181
  • Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain OCT. Am J Ophthalmol. 2008;146:496-500

📘 Want the exam-ready deep dive? This topic is covered in iNotes 2027: Basic Science & Optics (Ophthalmology Postgraduate Exam Notes) — available on Kindle. See all my books.

Written and medically reviewed by Dr. Dhaval Patel, MD (Ophthalmology, AIIMS New Delhi) · Editorial policy

Consultant, Cataract & Refractive Surgery — among a small number of AIIMS-trained ophthalmologists practicing in Gujarat. Read full credentials & experience or view his 28 publications on ResearchGate.

📚 Also the author of OKAT Decoded, FRCOphth Decoded and other high-yield ophthalmology exam-prep books used by residents and PG aspirants.

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