Concentrically constricted visual field
Rust-colored corneal stromal staining
Pupillary mydriasis and poor reactivity
Brown deposits on the anterior lens
Peripheral retinal pigmentation (early)
Diffuse retinal pigmentation (late)
Narrowed retinal vessels
Optic disc discoloration and atrophy
Secondary open-angle glaucoma from iron accumulation in the trabecular meshwork
Electroretinogram (ERG) changes in siderosis include an increased a-wave and normal b-wave during the very early phase of toxicity, with a diminishing b-wave amplitude later. Eventually, the ERG may become extinguished.
Serial ERGs can be helpful for following eyes with small retained foreign bodies. If the b-wave amplitude decreases, removal of the foreign body generally is recommended
- compiled & published by Dr Dhaval Patel MD AIIMS
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