Hypertensive Retinopathy: Grading and Hypertensive Emergencies

Hypertensive Retinopathy: Grading and Hypertensive Emergencies

Last updated: November 2026

The retina is the only place where we can see small arteries directly, and hypertension changes them in a predictable sequence. Most findings are chronic and need a physician; a few signal a hypertensive emergency that needs the same-day attention of a medical team.

Grading

Wong–Mitchell (2004)SignsMeaning
NoneNo detectable signsLow risk
MildGeneralised or focal arteriolar narrowing, AV nicking, opacity of the arteriolar wall (copper or silver wiring)Modest association with stroke and heart disease
ModerateHaemorrhages (blot, dot, flame), microaneurysms, cotton wool spots, hard exudatesStrong association with stroke, cognitive decline and cardiovascular death
Malignant (accelerated)Moderate signs plus optic disc swellingHypertensive emergency: refer to the medical team the same day

The older Keith–Wagener–Barker classification (grades 1 to 4) is still asked in exams: grade 1 mild narrowing; grade 2 marked narrowing with AV nicking; grade 3 plus haemorrhages, exudates and cotton wool spots; grade 4 plus disc swelling.

Choroid and optic nerve

  • Hypertensive choroidopathy in acute severe hypertension (pre-eclampsia, phaeochromocytoma, renal crisis): Elschnig spots (yellow, later pigmented patches), Siegrist streaks along choroidal vessels, and serous retinal detachment.
  • Hypertensive optic neuropathy: bilateral disc swelling with a macular star; distinguish from papilloedema by the blood pressure.

In the clinic

  • Measure blood pressure in every patient with haemorrhages, cotton wool spots, vein occlusion or disc swelling.
  • BP of 180/120 mmHg or more with disc swelling or new organ damage is a hypertensive emergency: refer immediately. Blood pressure should be lowered in a controlled way by the medical team; very rapid lowering can cause optic nerve and brain ischaemia.
  • Associated conditions: retinal vein and artery occlusion, macroaneurysm, NAION.

Where residents slip

  • Calling bilateral disc swelling papilloedema without measuring the blood pressure.
  • Forgetting pre-eclampsia in a pregnant woman with serous retinal detachment.
  • Advising rapid BP reduction from the eye clinic.

Test yourself: flip cards

Related: Retinal Vein Occlusion, Papilledema vs Pseudopapilledema, Medical Fitness Before Eye Surgery: BP, Sugar, Tamsulosin, GLP-1 and SGLT2.

Key sources

  • Wong TY, Mitchell P. Hypertensive retinopathy. N Engl J Med. 2004;351:2310-2317
  • Keith NM, Wagener HP, Barker NW. Some different types of essential hypertension: their course and prognosis. Am J Med Sci. 1939;197:332-343

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Written by Dr. Dhaval Patel, MD (Ophthalmology, AIIMS New Delhi)

Consultant, Cataract & Refractive Surgery — among a small number of AIIMS-trained ophthalmologists practicing in Gujarat. Read full credentials & experience or view his 28 publications on ResearchGate.

📚 Also the author of OKAT Decoded and other high-yield ophthalmology exam-prep books used by residents and PG aspirants.

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