Eales Disease

Important Percentages

  • NVI: 0.5-0.8 %
  • NVD: 10-18 %
  • NVE: 50 %
  • Sec RRD: 8-11 %
   

Proliferative vascular retinopathy mimicking eales

  • SYSTEMIC: DM, Sarcoidosis, Sickle
  • OCULAR: BRVO, CRVO, Coats, Pars Planitis, ROP
 

Main causes of vision loss in Eales’ Disease

  • SUDDEN
    • Vitreous hemorrhage (NVE, Inflammatory BRVO, NVD)
    • Secondary rhegmatogenous retinal detachment
 

GRADUAL

  • Macular edema
  • Traction retinal detachment involving posterior pole
  • Disc edema
  • Multiple vitreous membranes
  • Cataract
  • Glaucoma – NVG/Ghost cell
  • Optic atrophy
  • Epimacular membrane
 

Main indications for vitrectomy in Eales’ disease

  • Non-resolving vitreous hemorrhage
  • Traction retinal detachment involving posterior pole
  • Multiple vitreous membranes
  • Combined traction and rhegmatogenous retinal detachment
  • Vitreous hemorrhage associated with hemolytic or ghost-cell glaucoma
  • Macular pucker / Epimacular membrane
  • Vitreous hemorrhage associated with rubeosis
 

Management

  • If B/L: Systemic Steroids
  • If U/L:
    • <2 quadrent: PST
    •           
    • >2 quadrent: Systemic Steroids
 

- compiled & published by Dr Dhaval Patel MD AIIMS